SELECTED PUBLICATIONS

CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent KATP channel closure

Sdao SM, Ho T, Poudel C, Foster HR, De Leon ER, Adams MT, Lee JH, Blum B, Rane SG, and Merrins MJ.

Cell Reports. 2021.​ 

What Regulates Basal Insulin Secretion and Causes Hyperinsulinemia?

Corkey BE, Deeney JT, and Merrins MJ.

Diabetes. 2021.​ 

Pyruvate Kinase Controls Signal Strength

in the Insulin Secretory Pathway

Lewandowski SL†, Cardone RL†, Foster HR†, Ho T, Potapenko E, Poudel C, VanDeusen HR, Sdao SM, Alves TC, Zhao X, Capozzi ME, De Souza AH, Jahan I, Nunemaker CS, Davis DB, Campbell JE, Kibbey RG*, and Merrins MJ*.

Cell Metabolism. 2020.​

Accelerating multi-tissue phosphoenolpyruvate cycling

improves metabolic homeostasis

Abulizi A, Cardone RL, Lewandowski SL, Zhao SL, Alves TC, Thomas C, Kung C, Wang B, Rahimi Y, Seibel S, Andrews Z, Merrins MJ and Kibbey RG.

Cell Metabolism. 2020.​ 

Targeting Pyruvate Kinase PEPs Up Insulin Secretion and Improves Glucose Homeostasis

Corkey BE.

Cell Metabolism. 2020.​ 

Designing a Compact, Low-Cost FRET Microscopy Platform for the Undergraduate Classroom

Rupel JW†, Sdao SM†, Johnston KE, Nethery ET, Gabardi KA, Ratliff BA, Simmons BJ, Postlewaite JT, Kita AM, Rogers JD*, and Merrins MJ*.​

The Biophysicist. 2020.​

Obesity-Dependent CDK1 Signaling Stimulates Mitochondrial Respiration at Complex I in Pancreatic β-cells

Gregg T†, Sdao SM†, Dhillon RS, Rensvold JW, Lewandowski SL, Pagliarini DJ, Denu JM, and Merrins MJ.​

Journal of Biological Chemistry. 2019.​

Age-Dependent Protection of Insulin Secretion

in Diet Induced Obese Mice

De Leon ER, Gregg TA, Brinkman J, Fenske RJ, Schmidt BA, Kimple ME, Lamming DW*, and Merrins MJ*.

Scientific Reports. 2018.​ 

Radiomanganese PET Detects Changes in Functional β-cell Mass in Mouse Models of Diabetes

Hernandez R†, Graves SA†, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ*, Cai W*.

Diabetes. 2017.

Pancreatic β-cells From Mice Offset Age-Associated Mitochondrial Deficiency With Reduced KATP Channel Activity.

Gregg T†, Poudel C†, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW*, Merrins MJ*.​

Diabetes. 2016.